A number of viral diseases, such as dengue, Zika, Chikungunya, and yellow fever are transmitted to humans by the same intermediary: the Aedes aegypti mosquito. However, like other insects, this mosquito possesses antiviral defenses based the mechanism of RNA interference: small RNA molecules that can specifically degrade the genetic material of the virus, thereby blocking its multiplication and dissemination in the organism.
Yet why is this system seemingly incapable of stopping dengue virus in the Aedes mosquito? Without it, the viruses in the blood on which the mosquito feeds can multiply and subsequently infect its salivary glands.
Aedes then transmits this virus during its next meal. Surprisingly, Loqs2 is not present in the genome of other related mosquitoes, which are not vectors of the virus. Researchers deduced that this gene could provide a key to understanding this distinctive feature of Aedes mosquitoes. Control of dengue virus in the midgut of Aedes aegypti by ectopic expression of the dsRNA-binding protein Loqs2.
Roenick P. Olmo, Alvaro G. Dengue fever, also known as breakbone fever, is a mosquito-borne infection that can lead to a severe flu-like illness.
It is caused by four different viruses and spread by Aedes mosquitoes. Symptoms range from mild to severe. These usually require hospitalization. There are currently no vaccines. The best method of prevention is to avoid mosquito bites. Dengue fever is rare in the United States U. Outbreaks have occurred in Texas, Florida, and Hawaii. Symptoms usually disappear after a week, and mild dengue rarely involves serious or fatal complications. At first, symptoms of DHF may be mild, but they gradually worsen within a few days.
As well as mild dengue symptoms, there may be signs of internal bleeding. Dengue is a virus, so there is no specific treatment or cure.
However, intervention can help, depending on how severe the disease is. Preventing dehydration : A high fever and vomiting can dehydrate the body. The person should drink clean water, ideally bottled rather than tap water. Rehydration salts can also help replace fluids and minerals. Painkillers, such as Tylenol or paracetamol : These can help lower fever and ease pain. Non-steroidal anti-inflammatory drugs NSAIDs , such as aspirin or ibuprofen, are not advised, as they can increase the risk of internal bleeding.
There are four dengue viruses DENV that cause dengue fever. They are all spread by a species of mosquito known as Aedes aegypti , and more rarely by the Aedes albopictus mosquito. The viruses jumped from monkeys to humans between and years ago , according to the CDC, but dengue remained a minor problem until the middle of the twentieth century. Aedes aegypti originated in Africa, but nowadays it is found in tropical areas around the world, especially in and around areas of human population.
There are not yet any approved vaccines to prevent infection with dengue virus. Since cases of dengue appearing in New York are imported, preventive measures are advised for travelers going to affected areas to minimize exposure to mosquitoes. The most effective protective measures are those that avoid mosquito bites. Use of insect repellents may be helpful in minimizing exposure. More information on repellents can be found at Environmental Protection Agency - insect-repellents.
Navigation menu. What is dengue hemorrhagic fever? Who gets dengue? How is dengue spread? What are the signs and symptoms of dengue fever? How is dengue fever diagnosed? What is the treatment for dengue fever? Does past infection with dengue virus make a person immune?
What can be done to prevent the spread of dengue fever? In addition: Be sure to follow label directions. Try to reduce the use of repellents by dressing in long sleeves and pants tucked into socks or boots.
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